Since the Ms 7.0 earthquake occurred in Lushan on April 20, 2013, five years after the Wenchuan Ms 8.0 earthquake, the seismogenic potential of southern Longmen Shan has been a considerable concern. Comparative studies of active faults and deep structures of the Lushan and Wenchuan earthquakes are important to evaluate Longmen Shan potential. Terrace measurements, geophysical surveys and borehole drilling reveal that late Quaternary fault activity in the southern segment of the Longmen Shan thrust belt is weaker than that along the central segment. Magnetotelluric data across the southern segment of the Longmen Shan thrust belt show that the central fault and the front-range fault are the electrical boundaries of the crust and that the Longmen Shan thrust belt is a high-resistivity body. The Lushan earthquake occurred at the boundary zone between the high- and low-resistivity bodies, and the crustal structure of the southern Longmen Shan thrust belt matches the multiunit combination seismogenic model, indicating a potential large earthquake in Longmen Shan. Compared to conditions along the central segment, the low-resistivity layer of the upper and lower crust on the western side of the Songpan-Ganzi block develops along the Xianshuihe fault, which may reduce the strain accumulated from the Songpan-Ganzi block to the southern Longmen Shan thrust belt. This interpretation suggests that the main crustal shortening is accommodated by foreland thin fold structures, whereas the structural deformation accommodated by the thrust belt accounts for only a small proportion; thus, the seismogenic potential of southern Longmen Shan is weaker than that of the central segment.